Pile foundations are essential to transmit structural loads to the underlying soils and rocks. Piles may functionally or accidently be subjected to lateral soil movements, most often due to the slope's failing nature, deep excavation, soil liquefaction and seismic activities, which significantly affect its stability and safety. This study uses PLAXIS 3D software to predict the response of pile foundations subjected to lateral soil movements. Two case studies were analysed to validate the predictive ability of the software, to test the sensitivity of the input parameters, and to serve as a practical guide for the selection of the parameters in case of lack of availability of complete in-situ information. The behaviour of soil-pile interaction in different types of soils, particularly clay soils, was also considered. The results underline the importance of advanced modelling and accurate parameter selection for the stability and reliability of pile foundations under passive loading and lateral soil movement conditions.